Tijaabada Cusub ee Hangzhou ayaa soo bandhigtay Alaab Cusub oo Baadhista Xayawaanka Samaynta Epoch - Canine iyo Feline Function 3-in-1 Kit Combo
Hangzhou New-Test Biotechnology Co., Ltd. ayaa si rasmi ah ugu dhawaaqday bilaabida laba nooc-samaynta alaabada cusub ee ogaanshaha xayawaanka ee suuqa caalamiga ah ee difaaca-diagnostic xayawaanka: Canine/Feline shaqada kelyaha ee Triple Test Kit (Creatinine/SDMA/CysC Triple Test) (Jaantuska 1 iyo Jaantuska 2), kaas oo keenaya xal cusub oo sax ah ogaanshaha caafimaadka xayawaanka iyo daaweynta.
Jaantuska 1 Xirmada tijaabada kelyaha ee saddex-geesoodka ah
Bishii Oktoobar 2022, New-Test Biotechnology Co., Ltd. ayaa ahayd tii ugu horreysay ee soo saarta falanqeeye Multi-channel Multi-channel Fluorescence immunoassay analyzer, NTIMM4 (jiilka saddexaad, eeg Jaantuska 3), iyo 2024-ka, kan cusub ee hal-channel multiplex immunofluorescence analyzer, NTIMM2 (jiilka afraad, eeg sawirka 4). Qalabkii ugu dambeeyay ee canine/feline kalyaha 3-in-1 xirmada tijaabada combo ayaa ku haboon labada nooc.
Jaantuska 3 NTIMM4 Jaantuska 4 NTIMM2
Ku takhasusay cilmi-baarista baarista molecule yar yar iyo horumarinta muddo lix sano ah, badeecooyin cusub ayaa la bilaabay.
Saxnaanta ogaanshaha molecule yar ayaa had iyo jeer ahaa caqabad si looga gudbo goobta tijaabada POCT, sidoo kale waa jihada cilmi baarista iyo horumarinta ee Nest-Test Bio loo qoondeeyay tan iyo markii la aasaasay in ka badan 6 sano ka hor. Daminta jidhka iyo dabeecadaha qudhunka ee alaabada fluorescent ee dhaqameed waxay si toos ah u saameeyaan saxnaanta natiijooyinka ogaanshaha molecule yar. Tignoolajiyada calaamadaynta naadirka dhulka ee naadirka ah, jiilka afraad ee nanomaterials fluorescent nanomaterials ee ay samaysay New-Test, ayaa loo aqoonsaday inay tahay nanomaterial fluorescent ugu xasilloon suuqa, kaas oo faa'iido u leh inuu ka gudbo astaamaha jireed ee deminta iftiinka. Marka lagu daro dhowr sano oo si joogto ah u wanaajinta habka, waxay ugu dambeyntii xallisay dhibaatada adduunka ee saxnaanta liidata ee POCT ee tijaabada molecule yar. Riixitaanka ugu horreeya waa xirmada baaritaanka saddex-laab ee shaqada kelyaha. Waxay dammaanad qaadaysaa saxnaanta iyo xasilloonida labada molecules yaryar (creatinine & SDMA) reagents ogaanshaha muddo 2 sano ah gudahood.
"Tijaabada kelida ah sidoo kale waa la heli karaa, haddaba maxaa loo sameeyay triad function kelyaha---Background of horumarka shaqada kelyaha ee saddex-geesoodka ah
Hadda, tilmaamayaasha caadiga ah ee shaqada kelyaha ee aan caadiga ahayn ee eeyaha iyo bisadaha waxaa ka mid ah creatinine (CREA) iyo urea nitrogen ee biochemistry; CysC (cystatin C) iyo asymmetric dimethylarginine (SDMA) ee tilmaamayaasha difaaca, iwm. Hadda, waxaa guud ahaan la rumeysan yahay in dhammaan tilmaamayaasha kor ku xusan lagu sifeeyo glomerulus. Marka heerka sifaynta glomerular uu hoos u dhaco dhaawaca kelyaha dartiis, tilmaamayaashani waxay ku ururi doonaan dhiigga waxayna kordhin doonaan feejignaanta, sidaas darteed waxay ka tarjumaysaa heerka naafanimada shaqada kelyaha. Bulshada Caalamiga ah ee Cilmi-baarista Cudurada Kelyaha (IRIS) nidaamka qiimeynta waxay u kala saartaa naafanimada kelyaha ee bisadaha afar darajo oo ku salaysan qiimaha creatinine (Fasalka I, caadi ama khafiif ah: <1.6 mg/dL; Fasalka II, dhexdhexaad: 1.6-2.8 mg /dL; Fasalka III, daran: 2.8-5.0 mg/dL; iyo Fasalka IV, heerka dhamaadka: > 5.0 mg/dL).
Naafanimada kelyaha ee eyda waxaa loo kala saaraa afar darajo (Darajada I, caadi ama khafiif: <1.4 mg/dL: Fasalka II, dhexdhexaad: 1.4-2.0 mg/dL: Fasalka III, daran: 2.0-4.0 mg/dL: Fasalka IV, iyo heerka dhamaadka:>4.0 mg/dL). Si kastaba ha ahaatee, sababtoo ah dareenka xaddidan ee creatinine ee xanuunka kelyaha ee hore ee dabadheeraad ah (CKD), calaamad kale oo xitaa hore oo ah sifaynta shaqada nephron, "symmetric dimethylarginine (SDMA)", ayaa la isticmaalay. Marka loo eego xogta, SDMA waxay muujin kartaa cillado aan caadi ahayn 25-40% ee kelyaha daciifka ah, halka creatinine loo arko inay tahay mid aan caadi ahayn 75% naafanimada.
CysC (cystatin C) waa cysteine protease inhibitor, miisaan yar oo kelli ah (13.3 kD), borotiinka aasaasiga ah ee aan glycosylated ahayn. Waa mid ka mid ah calaamadaha ugu badan ee la isticmaalo ee shaqada kelyaha hore ee daawaynta aadanaha. Sida creatinine iyo SDMA, waxaa lagu sifeeyaa glomerulus, laakiin way ka duwan tahay creatinine iyo SDMA in dheef-shiid kiimikaadku aanu ahayn marinka kaadi mareenka, laakiin gabi ahaanba waa la dheefshiido dib u nuugista iyada oo loo marayo tubules kelyaha. Hore looma ogaanin, taasoo keentay culimo badan, khubaro iyo suugaan laba gunaanad oo kala duwan oo ku saabsan dhaawaca kelyaha ee daba-dheeraada ee bisadaha: qaar waxay aaminsan yihiin in CysC ay tahay calaamad hore oo ah dhaawaca kelyaha ee joogtada ah waxaa loo isticmaali karaa eeyaha iyo bisadaha labadaba, halka kuwa kalena ay aaminsan yihiin in CysC ay si dhexdhexaad ah ula xiriirto CKD canine, laakiin si liidata bisadaha.
Waa maxay sababta ay u jiraan laba gunaanad oo iska soo horjeeda oo ka yimid isla "tusaha shaqada sifaynta glomerular"?
Sababtu waa Anuria, oo ah xaalad aad ugu badan bisadaha marka loo eego noocyada kale, gaar ahaan bisadaha labka ah. Xogta qaar waxay muujinaysaa in dhacdooyinka Anuria ee bisadaha labka ahi ay aad u sarreeyaan ilaa 68.6%, Anuria waxay si toos ah u keeni doontaa xannibaadda soo saarista creatinine, nitrogen urea dhiig iyo SDMA. Noolaha ayaa si joogto ah u dheefshiidka oo soo saara creatinine cusub, urea nitrogen iyo SDMA, marka la ogaado dhammaan saddexda tilmaame ee dhiigga wakhtigan, waxaa jiri doona koror xoog leh ama xitaa dillaaca tilmaamayaasha iyada oo aan loo eegin haddii glomerulus dhab ahaantii waxyeello u geystay.
CysC waxay leedahay qiimaheeda gaarka ah waqtigan, inkasta oo tilmaamayaashani yahay shaandhaynta glomerular, kuma eka kaadidu, waa iyada oo loo sii marayo tuubada dib u nuugista. Marka Anuria ay dhacdo laakiin shaqada kelyaha ay caadi tahay, tusmada CysC weli waxaa lagu sii hayn karaa heer caadi ah. Kaliya marka glomerulus ama burburka tuubada uu dhaco, tusmada CysC ayaa sare loogu qaadi doonaa mid aan caadi ahayn. Sidaa darteed, ogaanshaha dhammaan saddexda tusmooyinku waxay samayn karaan baadhitaan sax ah waxayna bixiyaan daaweynta u dhiganta si dhakhso ah oo hufan.
Tijaabada cusub ee shaqada kelyaha ee 3-in-1 xirmooyinka tijaabada ayaa siinaya muhiimad caafimaad oo cusub ogaanshaha dhaawaca kelyaha ee eeyaha iyo bisadaha!
Sharaxaadda mabaadi'da iyo isku-darka sifooyinka tilmaamayaasha, Tijaabada Cusub ee shaqada kelyaha ee 3-in-1 xirmooyinka tijaabada ayaa ku dhashay muhiimad caafimaad oo muhiim u ah eeyaha iyo bisadaha (gaar ahaan bisadaha) Anuria:
Tijaabo-cusub calaamadeeyaha shaqada kelyaha ee 3-in-1 xirmooyinka tijaabada ayaa loo isticmaalaa si loo kala saaro haddii uu jiro dhaawac dhab ah oo shaqeynaya kelyaha ee xaaladda Anuria ama taasoo keentay xannibaadda sare u kaca tusmooyinka Anuria. Dhaawaca shaqada dhabta ah ee kelyaha wuxuu u baahan yahay oo kaliya kateeteraynta kaadida iyo daryeelka la xidhiidha, saadaashana guud ahaan waa ka fiican tahay. Kor u qaadista tusmooyinka waxay u baahan tahay ma aha oo kaliya kateetarka kaadi mareenka iyo daaweynta anti-bararka, laakiin sidoo kale daaweynta la xidhiidha cudurrada kelyaha, iyo saadaalintu waa mid dhib badan, waxayna u badan tahay inay isu beddesho cudur kelyo ah oo daba-dheeraaday.
Hoos waxaa ah calaamadaynta cusub-Tijaabi shaqada kelyaha ee xogta xirmooyinka 3-in-1 ee Anuria caadiga ah (dhaawaca kelyaha ee aan dhabta ahayn) iyo dhaawaca kelyaha ee Anuria + ee kiisaska cusub ee cilmi baarista kiliinikada:
| Ogaanshaha Anuria Tijaabi cusub ee shaqada kelyaha 3-in-1 xirmooyinka tijaabada | Mashruuca | Natiijada | Natiijada |
| Creatinine | + | + | |
| SDMA | + | + | |
| CysC | + | - | |
| Gabagabo | Anuria waxay keentay dhaawac kalyaha ah | Marxaladda hore ee Anuria iyo dhaawaca kelyaha ama Anuria oo aan weli gaarin dhaawaca kelyaha |
Hoos waxaa ah qayb ka mid ah xogta caafimaad ee caadiga ah iyo sharraxaadda kiis ee shaqada kelyaha-Tijaabada Cusub ee 3-in-1 xirmooyinka tijaabada:
| Bisad | Taariikhda Caafimaadka | Calaamadaha Caafimaad | CysC (mg/L) | SDHA (ug/dL) | CR (mg/dL) | Gabagabo |
| 2024090902 | Cystitis/Dhaawac kelyaha oo daran | Xaalad maskaxeed oo xun, lumitaanka rabitaanka cuntada, Tusaha kelyaha ee aan caadiga ahayn, Anuria (xanuunnada kelyaha ee daba-dheeraada, anuria) | 1.09 | 86.47 | 8.18 | Dhaawaca kelyaha ee Anuria |
| 2024091201 | / | Xaalad maskaxeed oo xun, Anuria, shaqada kelyaha ee aan caadiga ahayn | 0.51 | 27.44 | 8.21 | Ma jiro dhaawac kelyo ah oo leh Anuria/Marxaladda hore |
| 2024092702 | / | Anuria | 0.31 | >100.00 | 9.04 | Ma jiro dhaawac kelyo ah oo leh Anuria/Marxaladda hore |
| 2024103101 | / | Anuria | 0.3 | 14.11 | 6.52 | Ma jiro dhaawac kelyo ah oo leh Anuria/Marxaladda hore |
| 2024112712 | Anuria | 0.5 | >100.00 | 8.85 | Ma jiro dhaawac kelyo ah oo leh Anuria/Marxaladda hore | |
| 2024112601 | Dysuria/Anuria | 0.43 | >100.00 | 9.06 | Ma jiro dhaawac kelyo ah oo leh Anuria/Marxaladda hore | |
| 0.47 | >100.00 | 878 | Ma jiro dhaawac kelyo ah oo leh Anuria/Marxaladda hore | |||
| 2024112712 | / | Anuria | 0.54 | 94.03 | 8.64 | Ma jiro dhaawac kelyo ah oo leh Anuria/Marxaladda hore |
Xaaladda Anuria, sababtoo ah kala duwanaanshaha habka dheef-shiid kiimikaadka gudaha ee tusaha kasta, waxaa jiri doona natiijooyin badan oo kala duwan oo loogu talagalay tusaha sifaynta shaqada kelyaha ee isku midka ah. Sidaa darteed, kala soocidda caadiga ah ee dhaawaca kelyaha ee creatinine ama SDMA hadda lama dabaqi karo, gabagabada caafimaad ee ugu dhowna waxaa lagu heli karaa oo keliya marka la isku daro falanqaynta iyo tilmaame kale "CysC". Waxaa lagu talinayaa in shaybaarada (cisbitaallada) ay dejiyaan heerar gudaha ah oo ku saleysan waayo-aragnimada bukaan-socodka, si loo sahamiyo muhiimada bukaan-socodka ee cusub iyo kuwa cusub.
Ugu dambayntii, New-Test Biotech waxa ay rajaynaysaa in maqaalkani uu tuuri doono leben si uu u soo jiito jaad, waxana uu rajaynaya in dawooyin badan oo Shiinaha ah oo dawooyinka xoolaha ah iyo soo saarayaasha ogaanshaha cudurka ay soo saari doonaan alaabo caafimaad oo muhiim ah isla markaana ay caawiyaan dhakhaatiir badan oo caafimaad oo gudaha ah si ay u gaadhaan heerka ugu sareeya adduunyo!
Lifaaqa: Aqbalaada Codsiga Patent ee Ilaalinta Hantida Caqliga
Waqtiga boostada: Jan-22-2025
